Bone Remodeling and the Microbiome
نویسندگان
چکیده
منابع مشابه
Bone Remodeling and Healing
To fulfill adequately their functions of support, sustentation and protection for the internal organs and guarantee blood calcium homeostasis, bone tissue is in constant remodeling. Alveolar bone, the primary support structure for teeth, is particularly subjected to continuous and fast remodeling associated with tooth eruption and positional adaptations, as well as with the functional demands o...
متن کاملnormAl bone remodelIng
Paget’s disease of bone (PDB) is a common disorder which may affect one or many bones. Although many patients are asymptomatic, a variety of symptoms and complications may occur. PDB is a focal disorder of bone turnover characterized by excessive bone resorption coupled with bone formation. PDB begins with a period of increased osteoclastic activity and bone resorption, followed by increased os...
متن کاملThe role of homocysteine in bone remodeling.
Bone remodeling is a very complex process. Homocysteine (Hcy) is known to modulate this process via several known mechanisms such as increase in osteoclast activity, decrease in osteoblast activity and direct action of Hcy on bone matrix. Evidence from previous studies further support a detrimental effect on bone via decrease in bone blood flow and an increase in matrix metalloproteinases (MMPs...
متن کاملAssessment of bone vascularization and its role in bone remodeling.
Bone is a composite organ that fulfils several interconnected functions, which may conflict with each other in pathological conditions. Bone vascularization is at the interface between these functions. The roles of bone vascularization are better documented in bone development, growth and modeling than in bone remodeling. However, every bone remodeling unit is associated with a capillary in bot...
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Vitamin A (retinol) is a necessary and important constituent of the body which is provided by food intake of retinyl esters and carotenoids. Vitamin A is known best for being important for vision, but in addition to the eye, vitamin A is necessary in numerous other organs in the body, including the skeleton. Vitamin A is converted to an active compound, all-trans-retinoic acid (ATRA), which is ...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Medicine
سال: 2017
ISSN: 2157-1422
DOI: 10.1101/cshperspect.a031203